Sourced material

Research reports

One topic per file, generated on a plan and a cadence, superseded rather than overwritten. This is what the domain dossiers are synthesized from.

A research report is the sourced material a domain dossier is synthesized from — generated on a plan and a cadence, one topic per file. A report carries no confidence tags. Its bracketed markers say who might have an incentive to shade a line; none of them says anyone checked it. To reach a score, a line has to be drafted onto a candidate as unverified and pass the Verifier or the Corroborator, like everything else.

canine equine distal limb wounds

Care pathway, site of service, and what is already in the room — canine equine distal limb wounds

canine-equine-distal-limb-wounds.care-pathway.care-pathway-overview2026-09-016 sourcesannual

Guideline position, pivotal evidence, effect sizes, negative findings — canine equine distal limb wounds

canine-equine-distal-limb-wounds.clinical-evidence.clinical-evidence-overview2026-09-016 sourcesquarterly

Which NPWT system the equine distal-limb comparative study used — canister-free single-use or conventional canistered

canine-equine-distal-limb-wounds.clinical-evidence.npwt-device-form-factor-equine-distal-limb-rct2026-09-207 sourcesannual

Condition, prevalence, incidence and trend direction — canine equine distal limb wounds

canine-equine-distal-limb-wounds.epidemiology.epidemiology-overview2026-09-016 sourcesannual

US pet insurance penetration among owned dogs

canine-equine-distal-limb-wounds.market-players.us-pet-insurance-penetration-dogs2026-09-134 sourcesmonthly

Major US veterinary distributor catalogs and canister-free NPWT — what is listed today

canine-equine-distal-limb-wounds.market-players.vet-distributor-npwt-listing2026-09-139 sourcesmonthly

US veterinary NPWT TAM — qualifying canine caseload, net unit price, obtainable specialty/referral share

canine-equine-distal-limb-wounds.market-players.vet-npwt-tam-caseload-price-share2026-09-136 sourcesmonthly

Reference products and why people stop using them — canine equine distal limb wounds

canine-equine-distal-limb-wounds.reference-products.reference-products-overview2026-09-016 sourcesquarterly

US pet insurer policy wording — invoice-based vs code-based adjudication, and whether NPWT/wound-care adjuncts are categorically excluded

canine-equine-distal-limb-wounds.reimbursement.pet-insurer-policy-wording-npwt-adjudication2026-09-207 sourcesannual

What changed in ten years and what is newly possible or cheap — canine equine distal limb wounds

canine-equine-distal-limb-wounds.technology.technology-overview2026-09-0111 sourcesannual

Prescriber, operator, purchaser, payer and patient — separate incentives — canine equine distal limb wounds

canine-equine-distal-limb-wounds.user-groups.user-groups-overview2026-09-017 sourcesquarterly

chronic subjective tinnitus neuromodulation

Care pathway, site of service, and what is already in the room — chronic subjective tinnitus neuromodulation

chronic-subjective-tinnitus-neuromodulation.care-pathway.care-pathway-overview2026-09-0112 sourcesannual

Guideline position, pivotal evidence, effect sizes, negative findings — chronic subjective tinnitus neuromodulation

chronic-subjective-tinnitus-neuromodulation.clinical-evidence.clinical-evidence-overview2026-09-0111 sourcesquarterly

Condition, prevalence, incidence and trend direction — chronic subjective tinnitus neuromodulation

chronic-subjective-tinnitus-neuromodulation.epidemiology.epidemiology-overview2026-09-017 sourcesannual

Entrants, exits, funding, launches, recalls — chronic subjective tinnitus neuromodulation

chronic-subjective-tinnitus-neuromodulation.market-players.market-players-overview2026-09-0111 sourcesmonthly

Reference products and why people stop using them — chronic subjective tinnitus neuromodulation

chronic-subjective-tinnitus-neuromodulation.reference-products.reference-products-overview2026-09-0112 sourcesquarterly

Codes, payment rates, coverage policy, and whose budget it comes from — chronic subjective tinnitus neuromodulation

chronic-subjective-tinnitus-neuromodulation.reimbursement.reimbursement-overview2026-09-016 sourcesquarterly

What changed in ten years and what is newly possible or cheap — chronic subjective tinnitus neuromodulation

chronic-subjective-tinnitus-neuromodulation.technology.technology-overview2026-09-0114 sourcesannual

Prescriber, operator, purchaser, payer and patient — separate incentives — chronic subjective tinnitus neuromodulation

chronic-subjective-tinnitus-neuromodulation.user-groups.user-groups-overview2026-09-017 sourcesquarterly

cross cutting

FDA's stated and exercised post-market enforcement posture toward animal-only devices

cross-cutting.fda-regulatory-posture.animal-device-postmarket-enforcement-practice2026-09-207 sourcesquarterly

FDA CPG 655.100 premarket exemption and FD&C Act post-market enforcement authority over animal-only devices

cross-cutting.fda-regulatory-posture.animal-device-premarket-exemption-cpg-655-1002026-09-137 sourcesquarterly

Veterinary NPWT device cost-of-goods and distributor margin stack at a $180-$320 practice price

cross-cutting.unit-economics.vet-npwt-cogs-distributor-margin2026-09-133 sourcesquarterly

ctdna mrd assay validation

Care pathway, site of service, and what is already in the room — ctdna mrd assay validation

ctdna-mrd-assay-validation.care-pathway.care-pathway-overview2026-09-0111 sourcesannual

ISO 17034 reference-material-producer accreditation in the US — accrediting bodies, fee schedules, timeline, and accredited producers of ctDNA material

ctdna-mrd-assay-validation.care-pathway.iso-17034-accreditation-cost-and-timeline2026-09-2513 sourcesannual

What ISO 17034, CAP MOL checklist and CLIA 493.1253 require, accept, or are silent on for third-party reference material in LoD validation

ctdna-mrd-assay-validation.care-pathway.iso-17034-and-cap-mol-reference-material-requirements2026-09-2511 sourcesannual

Guideline position, pivotal evidence, effect sizes, negative findings — ctDNA MRD assay validation

ctdna-mrd-assay-validation.clinical-evidence.clinical-evidence-overview2026-09-019 sourcesquarterly

"Commutability of ctDNA reference materials: native-plasma vs synthetic-matrix head-to-head and independent studies"

ctdna-mrd-assay-validation.clinical-evidence.native-vs-synthetic-matrix-commutability-studies2026-09-2513 sourcesannual

Condition, prevalence, incidence and trend direction — ctdna mrd assay validation

ctdna-mrd-assay-validation.epidemiology.epidemiology-overview2026-09-013 sourcesannual

Absolute MRD test volumes from Natera and Guardant SEC filings (10-K/10-Q), 2023-2026

ctdna-mrd-assay-validation.epidemiology.signatera-guardant-mrd-volumes-sec-filings2026-09-259 sourcesquarterly

"Patent landscape: native-fragmentomic contrived plasma matrices and ultra-low-VAF spike-in characterization methods"

ctdna-mrd-assay-validation.market-players.ctdna-reference-material-patent-landscape2026-09-259 sourcesquarterly

Entrants, exits, funding, launches, recalls — ctdna mrd assay validation

ctdna-mrd-assay-validation.market-players.market-players-overview2026-09-0110 sourcesmonthly

Enumeration of US laboratories offering or developing tumor-informed ctDNA MRD tests

ctdna-mrd-assay-validation.market-players.us-labs-offering-tumor-informed-mrd2026-09-2510 sourcesquarterly

List prices and pack formats of commercial ctDNA/cfDNA reference materials (SeraCare/LGC, Horizon/Revvity, Twist, others)

ctdna-mrd-assay-validation.reference-products.ctdna-reference-material-list-prices2026-09-2522 sourcesquarterly

Reference products and why people stop using them — ctDNA MRD assay validation

ctdna-mrd-assay-validation.reference-products.reference-products-overview2026-09-016 sourcesquarterly

Codes, payment rates, coverage policy, and whose budget it comes from — ctdna mrd assay validation

ctdna-mrd-assay-validation.reimbursement.reimbursement-overview2026-09-018 sourcesquarterly

Digital PCR value assignment at 0.001%-0.01% VAF — Poisson floor, input mass, replicate counts and published uncertainty budgets

ctdna-mrd-assay-validation.technology.dpcr-poisson-floor-ultra-low-vaf-value-assignment2026-09-2514 sourcesannual

What changed in ten years and what is newly possible or cheap — ctdna mrd assay validation

ctdna-mrd-assay-validation.technology.technology-overview2026-09-018 sourcesannual

"Sourcing pooled normal human donor plasma for diagnostic reference materials: suppliers, screening obligations, lot sizes and cfDNA background"

ctdna-mrd-assay-validation.user-groups.human-donor-plasma-sourcing-for-reference-materials2026-09-2613 sourcesannual

Prescriber, operator, purchaser, payer and patient — separate incentives — ctdna mrd assay validation

ctdna-mrd-assay-validation.user-groups.user-groups-overview2026-09-017 sourcesquarterly

feline ckd subcutaneous fluid therapy

Care pathway, site of service, and what is already in the room — feline ckd subcutaneous fluid therapy

feline-ckd-subcutaneous-fluid-therapy.care-pathway.care-pathway-overview2026-09-018 sourcesannual

Guideline position, pivotal evidence, effect sizes, negative findings — feline ckd subcutaneous fluid therapy

feline-ckd-subcutaneous-fluid-therapy.clinical-evidence.clinical-evidence-overview2026-09-017 sourcesquarterly

Condition, prevalence, incidence and trend direction — feline ckd subcutaneous fluid therapy

feline-ckd-subcutaneous-fluid-therapy.epidemiology.epidemiology-overview2026-09-016 sourcesannual

Reference products and why people stop using them — feline ckd subcutaneous fluid therapy

feline-ckd-subcutaneous-fluid-therapy.reference-products.reference-products-overview2026-09-017 sourcesquarterly

What changed in ten years and what is newly possible or cheap — feline CKD subcutaneous fluid therapy

feline-ckd-subcutaneous-fluid-therapy.technology.technology-overview2026-09-019 sourcesannual

Prescriber, operator, purchaser, payer and patient — separate incentives — feline ckd subcutaneous fluid therapy

feline-ckd-subcutaneous-fluid-therapy.user-groups.user-groups-overview2026-09-018 sourcesquarterly

internal hemorrhoids office based treatment

Care pathway, site of service, and what is already in the room — internal hemorrhoids office based treatment

internal-hemorrhoids-office-based-treatment.care-pathway.care-pathway-overview2026-09-019 sourcesannual

Guideline position, pivotal evidence, effect sizes, negative findings — internal hemorrhoids office based treatment

internal-hemorrhoids-office-based-treatment.clinical-evidence.clinical-evidence-overview2026-09-0110 sourcesquarterly

Condition, prevalence, incidence and trend direction — internal hemorrhoids office based treatment

internal-hemorrhoids-office-based-treatment.epidemiology.epidemiology-overview2026-09-017 sourcesannual

Entrants, exits, funding, launches, recalls — internal hemorrhoids office based treatment

internal-hemorrhoids-office-based-treatment.market-players.market-players-overview2026-09-0115 sourcesmonthly

Reference products and why people stop using them — internal hemorrhoids office based treatment

internal-hemorrhoids-office-based-treatment.reference-products.reference-products-overview2026-09-0116 sourcesquarterly

Codes, payment rates, coverage policy, and whose budget it comes from — internal hemorrhoids office based treatment

internal-hemorrhoids-office-based-treatment.reimbursement.reimbursement-overview2026-09-016 sourcesquarterly

What changed in ten years and what is newly possible or cheap — internal hemorrhoids office based treatment

internal-hemorrhoids-office-based-treatment.technology.technology-overview2026-09-0115 sourcesannual

Prescriber, operator, purchaser, payer and patient — separate incentives — internal hemorrhoids office based treatment

internal-hemorrhoids-office-based-treatment.user-groups.user-groups-overview2026-09-018 sourcesquarterly

lower extremity lymphedema compression therapy

Care pathway, site of service, and what is already in the room — lower extremity lymphedema compression therapy

lower-extremity-lymphedema-compression-therapy.care-pathway.care-pathway-overview2026-09-0110 sourcesannual

Guideline position, pivotal evidence, effect sizes, negative findings — lower extremity lymphedema compression therapy

lower-extremity-lymphedema-compression-therapy.clinical-evidence.clinical-evidence-overview2026-09-019 sourcesquarterly

Condition, prevalence, incidence and trend direction — lower extremity lymphedema

lower-extremity-lymphedema-compression-therapy.epidemiology.epidemiology-overview2026-09-017 sourcesannual

Entrants, exits, funding, launches, recalls — lower extremity lymphedema compression therapy

lower-extremity-lymphedema-compression-therapy.market-players.market-players-overview2026-09-0114 sourcesmonthly

Reference products and why people stop using them — lower extremity lymphedema compression therapy

lower-extremity-lymphedema-compression-therapy.reference-products.reference-products-overview2026-09-0113 sourcesquarterly

Codes, payment rates, coverage policy, and whose budget it comes from — lower extremity lymphedema compression therapy

lower-extremity-lymphedema-compression-therapy.reimbursement.reimbursement-overview2026-09-0111 sourcesquarterly

What changed in ten years and what is newly possible or cheap — lower extremity lymphedema compression therapy

lower-extremity-lymphedema-compression-therapy.technology.technology-overview2026-09-0115 sourcesannual

Prescriber, operator, purchaser, payer and patient — separate incentives — lower extremity lymphedema compression therapy

lower-extremity-lymphedema-compression-therapy.user-groups.user-groups-overview2026-09-0111 sourcesquarterly

neonatal hyperbilirubinemia home phototherapy

Care pathway, site of service, and what is already in the room — neonatal hyperbilirubinemia home phototherapy

neonatal-hyperbilirubinemia-home-phototherapy.care-pathway.care-pathway-overview2026-09-018 sourcesannual

Guideline position, pivotal evidence, effect sizes, negative findings — neonatal hyperbilirubinemia home phototherapy

neonatal-hyperbilirubinemia-home-phototherapy.clinical-evidence.clinical-evidence-overview2026-09-019 sourcesquarterly

Condition, prevalence, incidence and trend direction — neonatal hyperbilirubinemia home phototherapy

neonatal-hyperbilirubinemia-home-phototherapy.epidemiology.epidemiology-overview2026-09-016 sourcesannual

Entrants, exits, funding, launches, recalls — neonatal hyperbilirubinemia home phototherapy

neonatal-hyperbilirubinemia-home-phototherapy.market-players.market-players-overview2026-09-018 sourcesmonthly

Reference products and why people stop using them — neonatal hyperbilirubinemia home phototherapy

neonatal-hyperbilirubinemia-home-phototherapy.reference-products.reference-products-overview2026-09-016 sourcesquarterly

Codes, payment rates, coverage policy, and whose budget it comes from — neonatal hyperbilirubinemia home phototherapy

neonatal-hyperbilirubinemia-home-phototherapy.reimbursement.reimbursement-overview2026-09-016 sourcesquarterly

What changed in ten years and what is newly possible or cheap — neonatal hyperbilirubinemia home phototherapy

neonatal-hyperbilirubinemia-home-phototherapy.technology.technology-overview2026-09-0111 sourcesannual

Prescriber, operator, purchaser, payer and patient — separate incentives — neonatal hyperbilirubinemia home phototherapy

neonatal-hyperbilirubinemia-home-phototherapy.user-groups.user-groups-overview2026-09-018 sourcesquarterly

pediatric obstructive sleep apnea testing

Care pathway, site of service, and what is already in the room — pediatric obstructive sleep apnea testing

pediatric-obstructive-sleep-apnea-testing.care-pathway.care-pathway-overview2026-09-017 sourcesannual

Guideline position, pivotal evidence, effect sizes, negative findings — pediatric obstructive sleep apnea testing

pediatric-obstructive-sleep-apnea-testing.clinical-evidence.clinical-evidence-overview2026-09-0110 sourcesquarterly

Condition, prevalence, incidence and trend direction — pediatric obstructive sleep apnea testing

pediatric-obstructive-sleep-apnea-testing.epidemiology.epidemiology-overview2026-09-018 sourcesannual

US population aged 5-17 and the diagnosed/referred share — the denominator a pediatric OSA market model multiplies

pediatric-obstructive-sleep-apnea-testing.epidemiology.us-population-denominator-and-diagnosed-share2026-09-116 sourcesannual

Entrants, exits, funding, launches, recalls — pediatric obstructive sleep apnea testing

pediatric-obstructive-sleep-apnea-testing.market-players.market-players-overview2026-09-0113 sourcesmonthly

Reference products and why people stop using them — pediatric obstructive sleep apnea testing

pediatric-obstructive-sleep-apnea-testing.reference-products.reference-products-overview2026-09-0111 sourcesquarterly

Codes, payment rates, coverage policy, and whose budget it comes from — pediatric obstructive sleep apnea testing

pediatric-obstructive-sleep-apnea-testing.reimbursement.reimbursement-overview2026-09-015 sourcesquarterly

What changed in ten years and what is newly possible or cheap — pediatric obstructive sleep apnea testing

pediatric-obstructive-sleep-apnea-testing.technology.technology-overview2026-09-0115 sourcesannual

Prescriber, operator, purchaser, payer and patient — separate incentives — pediatric obstructive sleep apnea testing

pediatric-obstructive-sleep-apnea-testing.user-groups.user-groups-overview2026-09-0112 sourcesquarterly

pediatric persistent asthma home monitoring

Care pathway, site of service, and what is already in the room — pediatric persistent asthma home monitoring

pediatric-persistent-asthma-home-monitoring.care-pathway.care-pathway-overview2026-09-018 sourcesannual

Guideline position, pivotal evidence, effect sizes, negative findings — pediatric persistent asthma home monitoring

pediatric-persistent-asthma-home-monitoring.clinical-evidence.clinical-evidence-overview2026-09-017 sourcesquarterly

Condition, prevalence, incidence and trend direction — pediatric persistent asthma home monitoring

pediatric-persistent-asthma-home-monitoring.epidemiology.epidemiology-overview2026-09-016 sourcesannual

Entrants, exits, funding, launches, recalls — pediatric persistent asthma home monitoring

pediatric-persistent-asthma-home-monitoring.market-players.market-players-overview2026-09-0113 sourcesmonthly

Reference products and why people stop using them — pediatric persistent asthma home monitoring

pediatric-persistent-asthma-home-monitoring.reference-products.reference-products-overview2026-09-0110 sourcesquarterly

Codes, payment rates, coverage policy, and whose budget it comes from — pediatric persistent asthma home monitoring

pediatric-persistent-asthma-home-monitoring.reimbursement.reimbursement-overview2026-09-016 sourcesquarterly

What changed in ten years and what is newly possible or cheap — pediatric persistent asthma home monitoring

pediatric-persistent-asthma-home-monitoring.technology.technology-overview2026-09-0113 sourcesannual

Prescriber, operator, purchaser, payer and patient — separate incentives — pediatric persistent asthma home monitoring

pediatric-persistent-asthma-home-monitoring.user-groups.user-groups-overview2026-09-018 sourcesquarterly

potassium monitoring ckd

Care pathway, site of service, and what is already in the room — potassium monitoring ckd

potassium-monitoring-ckd.care-pathway.care-pathway-overview2026-09-019 sourcesannual

Guideline position, pivotal evidence, effect sizes, negative findings — potassium monitoring ckd

potassium-monitoring-ckd.clinical-evidence.clinical-evidence-overview2026-09-017 sourcesquarterly

Condition, prevalence, incidence and trend direction — CKD, heart failure and hyperkalemia in RAASi-monitored populations

potassium-monitoring-ckd.epidemiology.epidemiology-overview2026-09-016 sourcesannual

Market players in potassium and creatinine monitoring for RAASi titration — entrants, exits, funding, launches, recalls

potassium-monitoring-ckd.market-players.market-players-overview2026-09-0114 sourcesmonthly

Reference products for potassium and creatinine monitoring during RAASi titration — and why people stop using them

potassium-monitoring-ckd.reference-products.reference-products-overview2026-08-319 sourcesquarterly

Codes, payment rates, coverage policy, and whose budget it comes from — potassium monitoring ckd

potassium-monitoring-ckd.reimbursement.reimbursement-overview2026-09-019 sourcesquarterly

What changed in ten years and what is newly possible or cheap — potassium monitoring in CKD

potassium-monitoring-ckd.technology.technology-overview2026-09-018 sourcesannual

Prescriber, operator, purchaser, payer and patient — separate incentives — potassium monitoring ckd

potassium-monitoring-ckd.user-groups.user-groups-overview2026-09-017 sourcesquarterly

stress urinary incontinence

Care pathway, site of service, and what is already in the room — stress urinary incontinence

stress-urinary-incontinence.care-pathway.care-pathway-overview2026-09-017 sourcesannual

Guideline position, pivotal evidence, effect sizes, negative findings — stress urinary incontinence

stress-urinary-incontinence.clinical-evidence.clinical-evidence-overview2026-09-019 sourcesquarterly

Condition, prevalence, incidence and trend direction — stress urinary incontinence

stress-urinary-incontinence.epidemiology.epidemiology-overview2026-09-019 sourcesannual

Entrants, exits, funding, launches, recalls — stress urinary incontinence

stress-urinary-incontinence.market-players.market-players-overview2026-09-0114 sourcesmonthly

How manufacturers of home devices paid as Medicare capped-rental DMEPOS items have made per-beneficiary economics work

stress-urinary-incontinence.reference-products.analog-capped-rental-manufacturer-economics2026-09-3015 sourcesquarterly

What happened to prescribing of home devices whose coverage requires documented failure of a conservative trial

stress-urinary-incontinence.reference-products.analog-documented-conservative-failure-prescribing2026-09-3021 sourcesquarterly

Continuation of self-inserted intravaginal devices when a non-invasive alternative exists, and what raised it

stress-urinary-incontinence.reference-products.analog-self-inserted-device-continuation2026-09-3017 sourcesquarterly

Who has recorded a microvolt biosignal on the electrode that is simultaneously stimulating, and closed a therapy loop on it

stress-urinary-incontinence.reference-products.analog-sensing-while-stimulating2026-09-3024 sourcesquarterly

Reference products and why people stop using them — stress urinary incontinence

stress-urinary-incontinence.reference-products.reference-products-overview2026-09-017 sourcesquarterly

Codes, payment rates, coverage policy, and whose budget it comes from — stress urinary incontinence

stress-urinary-incontinence.reimbursement.reimbursement-overview2026-09-198 sourcesquarterly

What body systems the RTM device-supply codes reach, and whether pelvic floor is one of them — stress urinary incontinence

stress-urinary-incontinence.reimbursement.rtm-device-supply-code-scope2026-09-192 sourcesquarterly

What changed in ten years and what is newly possible or cheap — stress urinary incontinence

stress-urinary-incontinence.technology.technology-overview2026-09-019 sourcesannual

Prescriber, operator, purchaser, payer and patient — separate incentives — stress urinary incontinence

stress-urinary-incontinence.user-groups.user-groups-overview2026-09-016 sourcesquarterly

veterinary diabetes glucose monitoring

Care pathway, site of service, and what is already in the room — veterinary diabetes glucose monitoring

veterinary-diabetes-glucose-monitoring.care-pathway.care-pathway-overview2026-09-0110 sourcesannual

Guideline position, pivotal evidence, effect sizes, negative findings — veterinary diabetes glucose monitoring

veterinary-diabetes-glucose-monitoring.clinical-evidence.clinical-evidence-overview2026-09-016 sourcesquarterly

Condition, prevalence, incidence and trend direction — veterinary diabetes glucose monitoring

veterinary-diabetes-glucose-monitoring.epidemiology.epidemiology-overview2026-09-0110 sourcesannual

Reference products and why people stop using them — veterinary diabetes glucose monitoring

veterinary-diabetes-glucose-monitoring.reference-products.reference-products-overview2026-09-016 sourcesquarterly

What changed in ten years and what is newly possible or cheap — veterinary diabetes glucose monitoring

veterinary-diabetes-glucose-monitoring.technology.technology-overview2026-09-018 sourcesannual

Prescriber, operator, purchaser, payer and patient — separate incentives — veterinary diabetes glucose monitoring

veterinary-diabetes-glucose-monitoring.user-groups.user-groups-overview2026-09-019 sourcesquarterly